Two arts, architecture and music from the beginning of history, have always had a lively presence in human life, in so far as it is difficult to determine the priority of each of them. The comparative study of these two artistic fields brings together common elements in architecture and music and their relationship with each other. It should be noted that the spatial range studied in this study is Italy and Central and Western Europe. The aim of the research is to answer these questions: Is there any relationship between music and architecture principles and aesthetics of the above-mentioned period? And the assumption is that there is research. However, in this era in which architecture influenced the music, are there any common factors between these two fields of art? It is assumed that architecture and music have also influenced many common factors existing between them. Investigating the matter through library studies based on descriptive method using documents library and study architectural sample image and audio samples of music stude is done. The result of the comparative study of architecture and music in the world confirms the hypotheses in the present study and shows that these two domains have commonalities in common, and demonstrates that these common characteristics of the movement in the Renaissance, which indicates their interaction is mutual.